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. 2026 Jul 5;27(13):6036. doi: 10.3390/ijms27136036
API Active Pharmaceutical Ingredient
BGE Background Electrolyte
β-CD β-Cyclodextrin
CD Cyclodextrin
CE Capillary Electrophoresis
COSY Correlation Spectroscopy
DIPE Diisopropyl Ether
DIPEA N,N-diisopropylethylamine
DMF Dimethylformamide
DMSO Dimethyl Sulfoxide
DoE Design of Experiments
DS Degree of Substitution
ee Enantiomeric Excess
EMO Enantiomer Migration Order
HMBC Heteronuclear Multiple Bond Correlation
HOESY Heteronuclear Overhauser Effect Spectroscopy
HPLC High-Performance Liquid Chromatography
HP-β-CD Hydroxypropyl-β-Cyclodextrin
HSQC Heteronuclear Single Quantum Coherence
ICH International Council for Harmonisation
IDE Idelalisib
LOQ Limit of Quantification
LOD Limit of Detection
MeOH Methanol
NMR Nuclear Magnetic Resonance
NOESY Nuclear Overhauser Effect Spectroscopy
pD pH Measured in Deuterated Solvent
PI3Kδ Phosphoinositide 3-Kinase Delta
R-IDE R-Enantiomer of Idelalisib
ROESY Rotating-frame Overhauser Effect Spectroscopy
Rs Resolution
RSD Relative Standard Deviation
S-IDE S-Enantiomer of Idelalisib
TGA Therapeutic Goods Administration
UV Ultraviolet