Table 3.

Subgroup analysis.

Variable	Subgroups	Unweighted		Weighted
		n (total)	n (event_%)	SI, OR (95% CI)	P for interaction
Age					.137
< 65	Without DR	1791	109 (6.1)	Reference
	With DR	461	35 (7.6)	1.30 (0.79–2.16)
≥ 65	Without DR	1386	50 (3.6)	Reference
	With DR	368	27 (7.3)	2.64 (1.13–6.14)
Gender					.695
Male	Without DR	1599	63 (3.9)	Reference
	With DR	448	31 (6.9)	1.77 (0.93–3.35)
Female	Without DR	1578	96 (6.1)	Reference
	With DR	381	31 (8.1)	1.55 (0.85–2.83)
Hypertension					.141
No	Without DR	843	40 (4.7)	Reference
	With DR	168	13 (7.7)	3.62 (1.53–8.55)
Yes	Without DR	2334	119 (5.1)	Reference
	With DR	661	49 (7.4)	1.46 (0.89–2.39)
Congestive heart failure					.509
No	Without DR	2917	134 (4.6)	Reference
	With DR	688	48 (7.0)	1.53 (0.84–2.78)
Yes	Without DR	260	25 (9.6)	Reference
	With DR	141	14 (9.9)	3.71 (1.17–11.79)
Angina pectoris					.043
No	Without DR	2968	141 (4.8)	Reference
	With DR	747	58 (7.8)	1.88 (1.16–3.07)
Yes	Without DR	209	18 (8.6)	Reference
	With DR	82	4 (4.9)	0.24 (0.03–1.74)
Hyperlipidemia					.948
No	Without DR	461	28 (6.1)	Reference
	With DR	93	4 (4.3)	1.99 (0.46–8.59)
Yes	Without DR	2716	131 (4.8)	Reference
	With DR	736	58 (7.9)	1.70 (1.11–2.60)
Depression					.594
No	Without DR	2796	56 (2.0)	Reference
	With DR	694	22 (3.2)	1.45 (0.61–3.44)
Yes	Without DR	381	103 (27.0)	Reference
	With DR	135	40 (29.6)	2.11 (1.24–3.61)

Adjusted for age, gender, race, ethnicity, marital status, education level, BMI, MET, smoking, alcohol, hypertension, congestive heart failure, angina pectoris, hyperlipidemia, and depression.

BMI = body mass index, CI = confidence interval, DR = diabetic retinopathy, MET = metabolic equivalent task, OR = odds ratio, SI = suicidal ideation.