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. 2026 Jun 30;17:1826309. doi: 10.3389/fphys.2026.1826309

Table 2.

Metabolite markers that best (metabolite significant in the t-test, PLSDA, Venn diagram and effect size) describe the variation between the control and I. hoferi-infected White Stumpnose fish samples.

Compounds t-test
p-value
PLS-DA
VIP-value
Effect size
d-value
Positive fish
concentration (ng/μL)
Negative fish
concentration (ng/μL)
1, 2 Benzenedicarboxylic acid <0.05 7.970 0.651 1.726 ± 2.414 3.891 ± 1.512
Propanoic acid <0.05 5.134 0.571 0.304 ± 0.264 0.890 ± 0.319
Analyte 279 <0.05 6.617 0.561 0.636 ± 0.813 0.967 ± 0.237
D-mannose <0.05 2.187 0.541 15.082 ± 10.033 37.020 ± 20.777
Adipic acid <0.05 2.597 0.501 0.823 ± 0.513 1.277 ± 0.375