Fig. 7 Effect of the pump speed on the outflow-graft flow and blood pressure in patients with the Jarvik 2000. A) In 9 patients (20 studies), the average velocity–time integrals (VTIs) of diastolic, systolic, and total outflow-graft flow increased progressively as the pump speed increased, while the average S/D VTI ratio decreased. (S/D = systolic/diastolic; continuous line = systolic/diastolic VTI ratio; clear bars = systolic VTI; filled bars = diastolic VTI) B) The average systolic, diastolic, and mean blood pressures (BP) increased progressively and the average pulse pressure decreased as the pump speed increased. (Dotted line = mean blood pressure; continuous line = pulse pressure; clear bars = systolic blood pressure; filled bars = diastolic blood pressure)