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Long-patch BER activities on reduced AP site cccDNA for MGC nuclear extracts prepared from 3-month-old, 16-month-old, and 28-month-old male B6D2F1 mice. Results are presented as means ± SEM of assays for each of three independent nuclear extract preparations. Solid circles, 3-month-old mice; open circles, 16-month-old mice; solid squares, 28-month-old mice.
