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. 2006 Jan 21;332(7534):141–145. doi: 10.1136/bmj.38698.709572.55

Table 2.

Association between adverse events associated with warfarin and prescriptions for warfarin and ACE inhibitors in different comparison periods

Comparison period (days after exposure)
No of physicians evaluated
Odds ratio (95% Cl)
Warfarin use* ACE inhibitor use*
Bleeding analysis
0-90 530 0.79 (0.62 to 1.00) 1.13 (0.87 to 1.47)
91-180 521 0.60 (0.46 to 0.79) 1.16 (0.90 to 1.51)
181-270 488 0.61 (0.46 to 0.81) 1.11 (0.84 to 1.46)
271-360 469 0.72 (0.54 to 0.97) 1.06 (0.79 to 1.41)
Stroke analysis
0-90 704 0.95 (0.75 to 1.19) 0.88 (0.70 to 1.11)
91-180 664 1.05 (0.82 to 1.34) 0.99 (0.78 to 1.26)
181-270 656 1.22 (0.96 to 1.55) 1.17 (0.92 to 1.50)
271-360 621 1.23 (0.96 to 1.58) 1.08 (0.84 to 1.40)
*

Analyses adjusted for risk factors for stroke and bleeding as well as cardiology involvement in patient's care.