FIG. 6.

Role of hRPA in MMR. The DNA substrate was incubated with SS1 in the presence or absence of hRPA or SSB, as indicated, and products were analyzed by Southern blot hybridization. The membrane was probed with ³²P-labeled V1 (5′-AACGTCACCAATGAAACCAT-3′) (A) or ³²P-labeled C1 (5′-ATGGTTTCATTGGTGACGTT-3′) (B). APD, aphidicolin; HL, HeLa nuclear extract; Blank, reaction containing no protein; solid bars, ³²P-labeled probes.