Table 5.

Univariable and multivariable Logistic Regression Analyses: Factors associated with in-hospital mortality in HTLV-1-infected patients

Variable	Univariate analysis OR (95% CI)	P-value	Multivariable analysis OR (95% CI)	P-value	Reference / Unit of comparison
Age	1.015 (1.001–1.028)	0.030	1.000 (0.983–1.018)	0.961	Per 1-year increase
Sex (male)	0.560 (0.364–0.860)	0.010	0.725 (0.402–1.308)	0.286	Ref = female
Peripheral leukocytes	1.016 (1.007–1.025)	< 0.001	1.035 (1.016–1.055)	< 0.001	Per 1,000 / µL increase
Polymorphonuclears	1.018 (1.004–1.033)	0.013	1.034 (1.017–1.051)	< 0.001	Per 1% increase
Hemoglobin level	0.887 (0.811–0.969)	0.008	0.900 (0.801–1.011)	0.076	Per 1 g/dL increase
Platelet count	0.994 (0.992–0.997)	< 0.001	0.996 (0.993–0.999)	0.003	Per 1,000 / µL increase
Diabetes mellitus (yes)	1.565 (0.852–2.873)	0.170	—	—	Ref = no diabetes
HBV co-infection (yes)	3.000 (1.275–7.060)	0.023	3.823 (1.130–12.927)	0.031	Ref = no HBV co-infection
Myelopathy (present)	0.403 (0.236–0.685)	< 0.001	0.560 (0.276–1.135)	0.108	Ref = no myelopathy
Malignancy (present)	2.426 (1.572–3.745)	< 0.001	1.123 (0.239–5.278)	0.883	Ref = no malignancy
Chemotherapy (yes)	2.301 (1.484–3.566)	< 0.001	0.996 (0.204–4.862)	0.997	Ref = no chemotherapy
Diagnosis of infection as primary cause	1.918 (1.058–3.479)	0.032	—	—	Ref = non-infectious cause
Length of hospital stay	1.047 (1.024–1.071)	< 0.001	1.053 (1.022–1.085)	0.001	Per 1 day increase

Continuous variables are expressed per incremental unit of measurement (leukocytes and platelets = 1,000 cells/µL; hemoglobin = 1 g/dL; polymorphonuclears = 1% point; hospital stay = 1 day). For categorical variables, the reference groups are: female (sex), no diabetes, no HBV co-infection, no myelopathy, no malignancy, no chemotherapy, and non-infectious cause of admission. OR: odds ratio; CI: confidence interval; HBV: hepatitis B virus