Fig. 5.

IL7Rα is involved in miR-3614-5p-mediated inhibition of CRC progression in vitro. (A-C) CCK8, wound healing, and transwell assays were used to detect the effects of siRNA-mediated knockdown of IL7Rα on the proliferation, migration, and invasion of CRC cells, respectively. Scale bars = 500 μm (B) and 100 μm (C). (D-F) CCK8, wound healing, and transwell assays were performed to evaluate the effect of siRNA-IL7Rα on the increased proliferation, migration, and invasion of CRC cells induced by miR-3614-5p inhibitors. Scale bars = 500 μm (E) and 100 μm (F). (G-H) CCK8 and transwell assays were performed to detect the effect of IL7Rα upregulation on the decreased proliferation, migration, and invasion of CRC cells induced by miR-3614-5p mimics. Scale bars = 100 μm (H). *p < 0.05