TABLE 1.
kap121-34 mutationsa
| Nucleotide change | Position | Amino acid change | Position |
|---|---|---|---|
| A→C | 305 | I→T | 102 |
| A→G | 977 | D→G | 326 |
| T→C | 1087 | Y→H | 363 |
| A→G | 1274 | Q→R | 425 |
| A→T | 1336 | T→S | 446 |
| A→G | 1630 | K→E | 544 |
| T→G | 2042 | L→R | 681 |
| A→G | 2105 | E→G | 702 |
| T→C | 2317 | S→P | 773 |
| A→T | 2566 | N→Y | 856 |
| C→T | 2732 | S→F | 911 |
| T→C | 3068 | V→A | 1023 |
| A→G | 3109 | I→V | 1037 |
pkap121-34-TRP1 was isolated from kap121-34 cells, and the kap121-34 DNA sequence was determined by automated dideoxynucleotide chain termination sequencing. Presented are the nucleotide substitutions that result in predicted amino acid changes in Kap121p.