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. 2002 Apr;22(8):2821–2829. doi: 10.1128/MCB.22.8.2821-2829.2002

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Copyright © 2002, American Society for Microbiology

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FIG. 6. — Functional response to chronic hemodynamic stress induced by 3-week TAC compared to sham-operated littermates. (A and B) Basal left-ventricular contractility (A) and relaxation (B) rates were measured in microcatheterized intact animals. Values are in thousands. (C) Immunoblot analysis of heart extracts of sham-operated and TAC-treated mice, probed with the antibodies indicated on the left. CaM, calmodulin. (D) SERCA-2a and PLB levels in sham- and TAC-treated wild-type and S100A1 null mice. ∗∗, P < 0.001 versus wild type and heterozygotes.