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. 2002 Apr;22(8):2821–2829. doi: 10.1128/MCB.22.8.2821-2829.2002

FIG. 7.

FIG. 7.

Cardiac parameters in aged mice. (A and B) Basal and isoproterenol (2 ng)-stimulated inotropic (A) rates and lusitropic (B) rates in 16-month-old versus 5-month-old mice. Values are in thousands. (C) Left-ventricular cardiomyocyte cross-sectional areas in 16-month-old mice. (D) Left-ventricle end diastolic diameters (LVEDD) in groups of 10 mice per genotype from 10 weeks to 16 months of age. (E) Anterior wall diastolic thicknesses (AWDTh) in the same groups of animals shown in panel D. Posterior wall thicknesses were similar to those shown here (data not shown). ∗, P < 0.05 versus wild type.