TABLE 3.
Rb mutation rescues heart failure of E2f3−/− mice
| Age at death (days) | Deaths from heart failure/total no. of deaths of mice of genotype:
|
|
|---|---|---|
| E2f3−/− | Rb+/−E2f3−/− | |
| 200-250 | 1/1 | |
| 250-300 | 0/4 | |
| 300-350 | 2/3 | 0/6 |
| 350-400 | 1/1 | 0/6 |
| 400-450 | 1/1 | 0/5 |
| >450 | 2/4 | 0/4 |
| Total | 7/10 | 0/25 |