TABLE 1.

GzmA cleavage sites

Substrate	Cleavage site	Sequencea	Reference or source
pIL-1β	R120	DAPVR SLNCT	25
Thrombin receptor	R41	TLDPR SFLLR	52
Histone H1	K85	KLGLK SLVSK	68
Histone H2b	K12	APAPK KGSKK	68
SET	K176	QTQNK ASRKR	10
Lamin B	R392	VTVSR ASSSR	67
APE	K31	KTAAK KNDKE	Fan et al., submitted
HMG2	K65	EDMAK SDKAR

^aResidue in bold indicates the P₁ site for GzmA cleavage.