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. 2026 Jul 3;14:1850672. doi: 10.3389/fpubh.2026.1850672

Table 3.

Mediation role of CRP in the relationship between DII and fatigue.

Path Model
Direct paths
DII → CRP (a) 0.181***
CRP → fatigue (b) 0.233***
DII → fatigue (c′) 0.151***
Effect decomposition
Indirect effect (a × b) 0.042***
95% CI [0.020, 0.068]
Total effect 0.496***
Proportion mediated 8.50%

Unstandardized coefficients are reported. Standard errors are in parentheses. The models control for age, sex, smoking history, FEV1%, FCI, and activities. CI, confidence interval. ***p < 0.001.