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. 2002 May;22(9):3194–3203. doi: 10.1128/MCB.22.9.3194-3203.2002

FIG. 4.

FIG. 4.

Depletion of band III through RNAi inhibits in vitro RNA editing. Full round U deletion reaction at the first editing site of A6 pre-mRNA is shown. Reaction mixtures used equal amounts of protein (∼0.45 μg) from mitochondrial extracts (Ext) of the parental 29-13 cell line or independent clones of band III RNAi cells, either noninduced (−) or induced with tetracycline (Tet) for 6 days (+). The final −3 deletion product and the remaining 3′ cleavage fragment are seen.