TABLE 1.
Live recondensation of GFP-lac rep-ER-bound heterochromatic lac operator arrays induced by estradiol and antiestrogens in A03_1 cells
Treatment | % Original sizea | % SD | nb |
---|---|---|---|
10−9 M E2 (17β-estradiol) | 52 | 22 | 16 |
2 × 10−6 M trans-hydroxytamoxifen | 40 | 17 | 23 |
2 × 10−6 M ICI182,780 | 39 | 12 | 31 |
None | 116 | 27 | 13 |
Sizes of arrays were measured as in Fig. 3, and the size after 30 min of treatment was divided by the original size to determine the % original size.
n, number of cells examined.