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. 2026 Jul 6;13:1837424. doi: 10.3389/fnut.2026.1837424

Table 4.

Total GNRI levels and 28 day mortality in critically ill patients with prior or New AF.

MIMIC-IV Model 1 Model 2 Model 3
HR (95%CI) P HR (95%CI) P HR (95%CI) P
28 day mortality
All 0.99 (0.99 ~ 0.99)
p < 0.001
0.99 (0.99 ~ 0.99)
p < 0.001
0.99 (0.98 ~ 0.99)
p < 0.001
New-onset AF 0.99 (0.98 ~ 0.99)
p < 0.001
0.99 (0.98 ~ 0.99)
p < 0.001
0.99 (0.99 ~ 0.99)
P = 0.009
Prior AF 1.00 (0.99 ~ 1.00)
p = 0.178
0.99 (0.99 ~ 1.00)
p = 0.072
1.00 (0.99 ~ 1.01)
p = 0.761
Sepsis
All 0.99 (0.99 ~ 0.99)
P = 0.005
0.99 (0.99 ~ 0.99)
p < 0.001
0.99 (0.99 ~ 0.99)
p < 0.001
New-onset AF
Continuous 0.99 (0.98 ~ 0.99)
p < 0.001
0.99 (0.98 ~ 0.99)
p = 0.001
0.99 (0.98 ~ 0.99)
P = 0.028
Q1: GNRI < 90.85 1.00 (reference) 1.00 (reference) 1.00 (reference)
Q2: 90.85 ≤ GNRI < 100.77 0.75 (0.56 ~ 1.00)
p = 0.052
0.90 (0.67 ~ 1.22)
p = 0.509
0.91 (0.67 ~ 1.24)
p = 0.541
Q3: 100.77 ≤ GNRI < 111.61 0.87 (0.65 ~ 1.15)
p = 0.316
0.94 (0.70 ~ 1.27)
p = 0.684
0.94 (0.70 ~ 1.28)
p = 0.711
Q4: GNRI ≥ 111.61 0.56 (0.41 ~ 0.76)
p < 0.001
0.64 (0.46 ~ 0.91)
p = 0.012
0.66 (0.46 ~ 0.93)
p = 0.019
Prior AF 1.00 (0.99 ~ 1.00)
p = 0.540
0.99 (0.99 ~ 1.00)
p = 0.118
1.00 (0.99 ~ 1.00)
p = 0.313
CRRT
All 1.00 (0.99 ~ 1.01)
p = 0.859
1.00 (0.99 ~ 1.01)
p = 0.706
1.00 (0.99 ~ 1.01)
p = 0.846
New-onset AF 1.01 (0.99 ~ 1.02)
p = 0.859
1.01 (0.99 ~ 1.02)
p = 0.262
1.01 (1.00 ~ 1.02)
p = 0.198
Prior AF 0.99 (0.97 ~ 1.00)
p = 0.133
0.99 (0.97 ~ 1.00)
p = 0.092
0.99 (0.97 ~ 1.00)
p = 0.109
Cardiac surgery
All 1.00 (0.98 ~ 1.02)
p = 0.817
1.00 (0.97 ~ 1.02)
p = 0.878
1.01 (0.99 ~ 1.04)
p = 0.320
New-onset AF 0.99 (0.97 ~ 1.01)
p = 0.308
0.99 (0.97 ~ 1.02)
p = 0.579
0.99 (0.97 ~ 1.01)
p = 0.479
Prior AF 1.07 (1.01 ~ 1.13)
p = 0.018
1.06 (1.01 ~ 1.11)
p = 0.019
1.05 (0.97 ~ 1.13)
p = 0.201

GNRI, Geriatric Nutrition Risk Index; HR, hazard ratio; CI, confidence interval; CRRT, continuous renal replacement therapy; AF, atrial fibrillation.