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. 2002 Jun;22(11):3942–3957. doi: 10.1128/MCB.22.11.3942-3957.2002

FIG. 1.

FIG. 1.

Characterization of the IRF-10 sequence. (A) Nucleotide and predicted amino acid sequences of chicken IRF-10 cDNA. The polyadenylation signal is doubly underlined. The last T nucleotide at position 1560 is followed in the pnl-b.pk0007.e2 clone by a tract of multiple A nucleotides. The 1,560-nt IRF-10 sequence plus the usual 200-nt poly(A) tract corresponds approximately to the 1.8- to 1.9-kb size of the IRF-10 mRNA estimated by Northern blot analysis (data not shown). (B) Sequence alignment of the predicted amino acid sequences of chicken IRF-10, IRF-4, and IRF-8. Light letters on a dark background identify identical amino acids. The lines under the sequences show the locations of the five functional regions of IRF family members. NT, N terminus; MR, middle region that includes the transactivation domain; CT, C terminus.