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. 2026 May 22;21:497. doi: 10.1186/s13019-026-04023-x

Table 2.

Results of univariate logistic regression analysis on 370 patients

Characteristic Non-LCS
[n = 335]
LCS
[n = 35]
OR 95% CI p-value
Age (Years) 70 (60, 75) 69 (64, 71) 1.00 0.96, 1.03 0.80
Sex
Male 141 (42%) 18 (51%) Reference - -
Female 194 (58%) 17 (49%) 0.69 0.34, 1.38 0.29
% FEV1 87 (73, 101) 81 (66, 91) 0.98 0.96, 1.00 0.035
% FVC 99 (88, 110) 86 (78, 98) 0.97 0.95, 0.99 0.001
TLCO 86 (71, 100) 91 (72, 100) 1.00 0.99, 1.02 0.81
Smoking Status
Non-Smoker 60 (18%) 6 (17%) Reference - -
Smoker 275 (82%) 29 (83%) 1.05 0.45, 2.91 0.91
Comorbidities
Absent 116 (35%) 4 (11%) Reference - -
Present 219 (65%) 31 (89%) 4.11 1.58, 14.0 0.002
Cancer Stage
1 230 (69%) 33 (94%) Reference - -
2 56 (17%) 1 (2.9%) 0.12 0.01, 0.60 0.002
3 28 (8.4) 0 (0%) 0.00 - -
4 21 (6.3%) 1 (2.9%) 0.33 0.02, 1.67 -
Surgery Type 0.059
Lobectomy 260 (78%) 21 (60%) Reference - -
Wedge 70 (21%) 12 (34%) 2.12 0.97, 4.46 -
Segmentectomy 5 (1.5%) 2 (5.7%) 4.95 0.68, 24.6 -
Surgical approach
Thoracotomy 85 (25%) 2 (5.7%) Reference - -
RATS/VATS 250 (75%) 33 (94%) 5.61 1.66, 35.1 0.003

OR; Odds Ratio, CI; Confidence Interval

LCS; Lung Cancer Screening, FEV1; Forced Expiratory Volume for 1 s, FVC; Forced Vital Capacity, TLCO; Transfer Factor for Carbon Monoxide VATS; Video-Assisted Thoracic Surgery, RATS; Robotic-Assisted Thoracic Surgery