TABLE 2.
Axial skeletal defects in newborn Sim2 mutants
| Defect | Genotype | No. affected/examined | Effecta |
|---|---|---|---|
| Scoliosis | +/+ | 1/14 | 1R |
| +/− | 10/21 | 4L/6R | |
| −/− | 11/24 | 5L/6R | |
| Rib protrusions | +/+ | 0/14 | |
| +/− | 5/21 | 2-5 | |
| −/− | 24/24 | 14-23 |
a
For scoliosis, the number of affected animals whose scoliosis displays left (L) or right (R) curvature is shown. For the rib protrusion defect, the range of numbers of protrusions found in these affected animals is shown. The numbers are based on visible protrusions per animal by alcian blue staining.