Table 2.
Multivariate analysis of the risk of gastric low-grade intraepithelial neoplasia upgrading/progression&.
| Variable | Regression coefficient (B) | SE | P | OR | 95% CI |
|---|---|---|---|---|---|
| Age, per year | 0.063 | 0.026 | 0.018 | 1.065 | 1.011–1.121 |
| Sex | |||||
| Female | 1 | ||||
| Male | 0.816 | 0.425 | 0.055 | 2.262 | 0.983–5.209 |
| History of eradication of H. pylori | |||||
| Uninfected | 1 | ||||
| Unsterilized | 0.780 | 0.460 | 0.090 | 2.182 | 0.885–5.381 |
| After sterilizing | 0.230 | 0.490 | 0.639 | 1.258 | 0.482–3.285 |
| Current H. pylori infection | |||||
| Negative | 1 | ||||
| Positive | 0.682 | 0.407 | 0.093 | 1.979 | 0.891–4.391 |
| Lesion size, per mm | 0.080 | 0.028 | 0.004 | 1.084 | 1.026–1.145 |
| Location | |||||
| Upper | 0.820 | 0.842 | 0.330 | 2.271 | 0.436–11.839 |
| Middle | −0.459 | 0.436 | 0.292 | 0.632 | 0.269–1.484 |
| Lower | 1 | ||||
| GA | |||||
| No | 1 | ||||
| Mild (C1.C2) | −1.529 | 1.785 | 0.392 | 0.217 | 0.007–7.175 |
| Moderate (C3.O1) | −1.772 | 1.787 | 0.321 | 0.170 | 0.005–5.646 |
| Severe (O2.O3) | −0.927 | 1.992 | 0.642 | 0.396 | 0.008–19.624 |
| IM | |||||
| IM2 | 1 | ||||
| IM1 | −0.824 | 0.912 | 0.366 | 0.439 | 0.073–2.621 |
| EF | |||||
| Absent | 1 | ||||
| Present | 1.172 | 0.582 | 0.044 | 3.229 | 1.031–10.108 |
| Kyoto gastritis score | 0.094 | 0.251 | 0.707 | 1.099 | 0.672–1.798 |
| Microsurface and microvascular | |||||
| Regular | 1 | ||||
| Irregular | 2.585 | 1.047 | 0.014 | 13.259 | 1.702–103.308 |
&Variables with an odds ratio (OR) of 1 were defined as reference categories.
Categorical variables were numerically coded as follows: sex (1 = male, 2 = female), H. pylori eradication history (0 = uninfected, 1 = unsterilized, 2 = after sterilizing), current H. pylori infection status (0 = negative, 1 = positive), lesion location (1 = upper stomach, 2 = middle stomach, 3 = lower stomach), gastric mucosal atrophy (0 = absent, 1 = mild [C1/C2], 2 = moderate [C3/O1], 3 = severe [O2/O3]), IM (1 = IM1, 2 = IM2), EF (0 = absent, 1 = present), and microsurface and microvascular patterns (1 = regular, 2 = irregular).