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. 2026 May 26;24:305. doi: 10.1186/s12957-026-04426-z

Table 3.

Results of the annual percentage change rate (AAPC) of the junction point regression analysis of the burden of breast cancer disease in each continent

Continent Cohort Range Lower Endpoint Upper Endpoint AAPC Lower CI Upper CI P–Value
Asia Prevalence Rate Full Range 1990 2021 –3.316* –3.336 –3.297 < 0.001
Death Rate Full Range 1990 2021 2.149* 2.131 2.168 < 0.001
Incidence Rate Full Range 1990 2021 –3.419* –3.441 –3.399 < 0.001
America Prevalence Rate Full Range 1990 2021 –0.710* –0.753 –0.664 < 0.001
Death Rate Full Range 1990 2021 –0.237* –0.279 –0.236 < 0.001
Incidence Rate Full Range 1990 2021 –0.689* –0.756 –0.619 < 0.001
Africa Prevalence Rate Full Range 1990 2021 2.215* 2.201 2.231 < 0.001
Death Rate Full Range 1990 2021 1.358* 1.341 1.378 < 0.001
Incidence Rate Full Range 1990 2021 2.249* 2.230 2.274 < 0.001
Oceania Prevalence Rate Full Range 1990 2021 0.983* 0.938 1.041 < 0.001
Death Rate Full Range 1990 2021 1.049* 1.004 1.097 < 0.001
Incidence Rate Full Range 1990 2021 0.951* 0.897 1.015 < 0.001
Europe Prevalence Rate Full Range 1990 2021 1.262* 1.230 1.286 < 0.001
Death Rate Full Range 1990 2021 0.256* 0.205 0.332 0.004
Incidence Rate Full Range 1990 2021 1.227* 1.185 1.266 < 0.001

* Indicates that the AAPC is significantly different from zero at the Inline graphic level