TABLE 1.
Enhanced frequency of erythromycin-resistant mutants in abf2Δ ntg1Δ and pif1Δ ntg1Δ double-mutant strains
| Strain | Avg no. of cells plated (108) | Avg. no. of erythromycin- resistant mutants | Mutant frequencya | Fold increaseb |
|---|---|---|---|---|
| NTG1 | 7.71 | 0.7 | 1.13 × 10−9 | 1 |
| ntg1Δ | 9.13 | 1.9 | 2.59 × 10−9 | 2.3 |
| pif1Δ | 5.69 | 16 | 3.34 × 10−8 | 29 |
| pif1Δ ntg1Δ | 5.28 | 31 | 6.35 × 10−8 | 56 |
| abf2Δ | 6.19 | 1.2 | 2.09 × 10−9 | 1.8 |
| abf2Δ ntg1Δ | 5.22 | 25 | 5.68 × 10−8 | 50 |
a
Calculated from the results of plating 25 to 30 independent cultures.
b
Calculated relative to the wild-type (NTG1) strain.