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. 2026 Jul 8;13:1856132. doi: 10.3389/fmed.2026.1856132

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Copyright © 2026 Gotur, Gowda, Pinkaew, Zhang, Hankins, Rodgers, Xu, Syed, Reddy, Zhao, Zheng, Folz, Mylonakis and Hamilton.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ROC curve line graph compares diagnostic performance of IL-10, IL-8, and IL-6, with corresponding AUC values of 0.75, 0.67, and 0.66. Axes show sensitivity versus one hundred percent minus specificity. — Receiver operating characteristic (ROC) curve analysis of plasma cytokines in COVID-19 ARDS patients. ROC curves illustrate the discriminatory performance of IL-10 (red), IL-8 (purple), and IL-6 (blue) for predicting invasive mechanical ventilation (IMV).