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. 2026 Jul 8;13:1856132. doi: 10.3389/fmed.2026.1856132

Figure 5.

Panel a presents a line graph comparing pct_CD57neg_NK cell percentages over time between non-IMV and IMV groups, highlighting p-values 0.031, 0.21, and 0.16 above the data points. Panel b shows a scatter plot with error bars of %CD57-NK cells out of CD45+ at Baseline, Day 4, and Day 8 for IMV (blue) and non-IMV (red) groups, indicating statistical significance at Baseline with an asterisk.

Immune cell phenotype analysis of CD57− NK cells in patients on IMV versus non-IMV. (a) Representative cytometry by time-of-flight (CyTOF) plots showing distribution of CD57− NK cells at baseline in patients requiring IMV compared with non-IMV group. (b) Quantitative analysis of CD57− NK cell frequencies within the CD45+ compartment at baseline. Non-IMV group demonstrated a significantly higher proportion of CD57− NK cells compared with IMV group, suggesting reduced NK cell senescence and preserved proliferative capacity in the non-IMV group. *p < 0.05.