Table 1.
Baseline characteristics of patients with COVID-19 ARDS.
| Variables | non-IMV | IMV | P-value |
|---|---|---|---|
| N | 25 | 11 | |
| Age (mean (SD)) | 61.92 (11.41) | 64.73 (10.46) | 0.49 |
| Gender – Male | 15 (60.0) | 7 (63.6) | 1.00 |
| BMI (mean (SD)) | 31.22 (6.72) | 31.27 (6.68) | 0.98 |
| Current smoker N (%) | 1 (4.0) | 0 (0.0) | 1.00 |
| Ex-smoker N (%) | 7 (28.0) | 2 (18.2) | 0.84 |
| CCI (mean (SD)) | 1.80 (1.89) | 2.18 (1.08) | 0.54 |
| Individual comorbid conditions N (%) | |||
| Hypertension | 14 (56.0) | 6 (54.5) | 1.00 |
| Diabetes mellitus II | 13 (52.0) | 4 (36.4) | 0.62 |
| Coronary artery disease | 3 (12.0) | 0 (0.0) | 0.59 |
| CHF – Heart failure | 3 (12.0) | 1 (9.1) | 1.00 |
| Hypersensitivity lung disease | 7 (28.0) | 1 (9.1) | 0.41 |
| Cerebrovascular accident | 2 (8.0) | 1 (9.1) | 1.00 |
| Cirrhosis | 2 (8.0) | 0 (0.0) | 0.86 |
| CKD – chronic kidney disease | 5 (20.0) | 0 (0.0) | 0.28 |
| ESRD – End-stage renal disease | 7 (28.0) | 2 (18.2) | 0.84 |
| COPD – Chronic obstructive pulmonary disease | 1 (4.0) | 0 (0.0) | 1.00 |
| Asthma | 1 (4.0) | 1 (9.1) | 1.00 |
| Active malignancy | 1 (4.0) | 2 (18.2) | 0.45 |
| Medications N (%) | |||
| ACE-I – Angiotensin-converting enzyme | 1 (4.0) | 2 (18.2) | 0.45 |
| ARB | 4 (16.0) | 1 (9.1) | 0.98 |
| Remdesivir | 14 (56.0) | 4 (36.4) | 0.47 |
| Hydroxychloroquine | 2 (8.0) | 0 (0.0) | 0.86 |
| Tocilizumab | 1 (4.0) | 2 (18.2) | 0.45 |
| Steroids | 24 (96.0) | 10 (90.9) | 1 |
| Convalescent – plasma | 0 (0.0) | 1 (9.1) | 0.669 |
| Antibiotics | 15 (60.0) | 7 (63.6) | 1 |
| Steroid – dose - per-day (mean (SD)) | 33.93 (25.97) | 9.17 (5.78) | <0.05 |
| Outcomes | |||
| 28th day mortality – N (%) | 3 (12.0) | 5 (45.5) | 0.07 |
| 30- day readmission – N (%) | 3 (12.0) | 1 (9.1) | 1 |
| Hospital – length-of-stay (mean (SD)) | 19.52 (12.44) | 43.00 (27.41) | 0.001 |
| ICU – length-of-stay (mean (SD)) | 9.12 (5.12) | 39.55 (27.75) | <0.001 |
Our study population consisted of 36 patients, of whom 11 belonged to the IMV group and 25 to the non-IMV group. IMV: Invasive Mechanical Ventilation, non-IMV: non-IMV: not on Invasive Mechanical Ventilation, N: total number of subjects, SD: Standard Deviation, BMI: Body Mass Index, CCI: Charlson Co-morbidity Index, CHF: Congestive Heart Failure, CKD: Chronic Kidney Disease, ESRD: End Stage Renal Disease, COPD: Chronic Obstructive Pulmonary Disease, ACE-I: Angiotensin Converting Enzyme Inhibitor, ARB: Angiotensin Receptor Blocker, ICU: Intensive Care Unit.