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. 2002 Jul;22(13):4836–4850. doi: 10.1128/MCB.22.13.4836-4850.2002

FIG. 5.

FIG. 5.

Chromosome rearrangements in the FS-1 and FS-2 subclones isolated from clone A211. Metaphase spreads from clone A211 (A) and its subclones FS-1 (B) and FS-2 (C) were hybridized with both chromosome 18-specific painting (red) and subtelomeric BAC 31E18 (green) probes (i). An enlarged view of the chromosome 18 homologues (ii) and reverse video of the blue channel showing the DAPI GC banding (iii) are also shown. A different metaphase spread hybridized with both chromosome-18-specific (red) and telomere-specific (green) probes is shown for clone A211 and its subclones, FS-1 and FS-2 (iv). The open arrows point to the normal chromosome-18 homologues, while the closed arrow points to the rearranged chromosome 18.