TABLE 2.
Distribution of β-galactosidase-positive progenitor cells in the bone marrow of SOCS-6−/− mice
| Stimulus | β-Galactosidase activity | % Distributiona
|
|||||
|---|---|---|---|---|---|---|---|
| Blast | G | GM | M | Eo | Meg | ||
| GM-CSF | Low | 4 | 0 | 3 | 10 | ||
| Medium | 47 | 18 | 20 | 33 | |||
| High | 48 | 82 | 77 | 57 | |||
| IL-3 | Low | 0 | 2 | 4 | 7 | 0 | 13 |
| Medium | 64 | 58 | 42 | 46 | 88 | 78 | |
| High | 36 | 40 | 54 | 47 | 12 | 9 | |
| G-CSF + SCF | Low | 4 | 9 | 12 | 18 | ||
| Medium | 35 | 40 | 20 | 12 | |||
| High | 61 | 51 | 68 | 71 | |||
a
Values are the percentages in each FACSgal fraction of the combined total number of colonies of each lineage present in the fractions. G, granulocytic; GM, granulocyte-macrophage; M, macrophage; Eo, eosinophil; Meg, megakaryocyte.