TABLE 2.
Biochemical parameters of mutant micea
| Mutation | Concn of:
|
|||
|---|---|---|---|---|
| ALT (U/liter) | Bilirubin U (mg/dl) | Bilirubin C (mg/dl) | Creatinine (mg/liter) | |
| MAAI | 20 ± 14 | <0.1 | <0.1 | 0.16 ± 0.05 |
| FAH | 78 ± 54 | 0.12 ± 0.4 | <0.1 | 0.25 ± 0.06 |
| MAAI/FAH | 75 ± 49 | <0.1 | 0.36 ± 0.7 | 1.42 ± 0.7 |
Six mice per group. Mice receiving NTBC were taken off NTBC for 6 days before harvesting. ALT, alanine transaminase; bilirubin U and C, free and conjugated bilirubin, respectively.