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. 2026 Jul 10;13:1803814. doi: 10.3389/fnut.2026.1803814

Table 2.

Effects of two types of eggs on glycolipid metabolism in diabetic patients after a 12-week intervention.

Indicator names Baseline Post-intervention p0 Baseline Post-intervention P0 P1’ Pinter
Among all individuals
SE egg (n = 27) ZE egg (n = 31)
Fasting insulin (mIU/L) 9.89 (7.47, 15.90) 6.73 (4.60, 14.07) 0.04 9.40 (5.33, 17.00) 8.22 (5.64, 17.30) 0.33 0.43 0.27
HOMA-IR 6.16 (4.53, 9.74) 2.79 (1.80, 6.55) 0.006 4.72 (2.63, 9.97) 2.79 (1.80, 6.54) 0.05 1.00 0.46
HOMA-β 20.98 (14.04, 38.01) 27.69 (15.96, 45.77) 0.78 22.48 (13.95, 32.32) 30.50 (16.08, 83.51) 0.06 0.34 0.12
TG (mmol/L) 1.62 (1.30, 2.74) 1.89 (1.14, 2.45) 0.25 2.00 (1.31, 2.64) 1.59 (1.13, 2.47) 0.0007 0.44 0.35
TC (mmol/L) 5.10 ± 0.99 5.31 ± 1.13 0.17 4.81 ± 0.98 4.87 ± 1.11 0.67 0.14 0.43
LDL-C (mmol/L) 2.79 ± 0.87 2.96 ± 0.92 0.22 2.48 ± 0.88 2.63 ± 0.86 0.14 0.17 0.93
HDL-C (mmol/L) 1.40 ± 0.40 1.46 ± 0.43 0.06 1.42 ± 0.39 1.42 ± 0.38 0.92 0.71 0.17
TyG 9.94 ± 0.62 9.54 ± 0.77 0.001 9.80 ± 0.57 9.30 ± 0.72 0.0001 0.22 0.49
Among patients with HbA1c < 8.9%
SE egg (n = 13) ZE egg (n = 14)
FBG (mmol/L) 13.19 ± 2.42 7.85 ± 2.08 0.0003 12.11 ± 1.72 7.40 ± 2.62 0.0002 0.63 0.65
HbA1c (%) 7.44 ± 0.69 7.65 ± 0.83 0.14 7.37 ± 0.88 7.29 ± 0.81 0.46 1.00 0.40
Fasting insulin (mIU/L) 14.00 (7.99, 33.25) 7.52 (5.24, 12.33) 0.03 15.00 (8.89, 61.95) 9.48 (6.16, 19.55) 0.08 0.16 0.92
HOMA-IR 7.80 (4.72, 22.5) 2.36 (1.72, 4.90) 0.01 8.74 (4.58, 30.06) 2.67 (1.98, 7.09) 0.02 0.47 0.96
HOMA-β 30.93 (19.94, 59.17) 35.21 (27.15, 51.42) 0.50 31.82 (21.48, 120.92) 71.87 (43.51, 146.77) 0.24 0.06 0.31
TG (mmol/L) 1.61 (1.06, 2.66) 1.93 (1.03, 2.34) 0.49 1.91 (1.39, 2.60) 1.39 (1.13, 2.47) 0.03 0.90 0.47
TC (mmol/L) 5.12 ± 0.70 5.30 ± 0.94 0.49 4.52 ± 0.52 4.46 ± 0.74 0.75 0.18 0.44
LDL-C (mmol/L) 2.80 ± 0.67 2.98 ± 0.77 0.47 2.25 ± 0.45 2.36 ± 0.59 0.39 0.22 0.79
HDL-C (mmol/L) 1.47 ± 0.41 1.51 ± 0.49 0.50 1.39 ± 0.37 1.37 ± 0.34 0.60 0.40 0.39
TyG 9.75 ± 0.50 9.17 ± 0.61 0.006 9.76 ± 0.37 9.03 ± 0.66 0.0005 0.56 0.50
Among patients with HbA1c ≥ 8.9%
SE egg (n = 14) ZE egg (n = 17)
FBG (mmol/L) 13.75 ± 2.16 12.06 ± 2.99 0.03 12.87 ± 2.62 11.10 ± 2.76 0.003 1.00 1.00
HbA1c (%) 9.61 ± 0.82 9.45 ± 0.90 0.39 10.13 ± 0.76 9.95 ± 1.31 0.38 0.96 1.00
Fasting insulin (mIU/L) 8.49 (6.37, 14.03) 5.83 (4.06, 18.08) 0.54 5.58 (4.04, 9.71) 6.97 (4.47, 11.87) 0.60 0.94 0.14
HOMA-IR 5.02 (4.09, 8.00) 3.19 (1.80, 10.30) 0.27 3.39 (2.38, 5.10) 2.78 (1.79, 6.42) 1.00 0.66 0.12
HOMA-β 16.90 (13.46, 24.81) 16.35 (10.18, 37.47) 0.71 14.81 (7.03, 23.82) 18.67 (15.65, 30.75) 0.16 0.74 0.16
TG (mmol/L) 1.92 (1.38, 3.26) 1.82 (1.23, 2.85) 0.41 2.27 (0.89, 2.83) 1.75 (0.92, 2.36) 0.02 0.50 0.56
TC (mmol/L) 5.09 ± 1.23 5.32 ± 1.31 0.20 5.06 ± 1.20 5.20 ± 1.27 0.45 0.80 0.73
LDL-C (mmol/L) 2.78 ± 1.04 2.93 ± 1.07 0.27 2.67 ± 1.10 2.86 ± 0.99 0.24 0.84 0.87
HDL-C (mmol/L) 1.33 ± 0.39 1.42 ± 0.38 0.05 1.44 ± 0.42 1.47 ± 0.42 0.51 0.75 0.27
TyG 10.11 ± 0.69 9.88 ± 0.76 0.10 9.84 ± 0.68 9.53 ± 0.70 0.006 0.20 0.66

SE egg, selenium-enriched egg. ZE egg, zeaxanthin-enriched egg. HOMA-IR, Homeostasis model assessment of insulin resistance index; HOMA-β, Homeostasis model assessment of β-cell function index; TG, triglyceride; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol. TyG, Triglyceride-glucose index; HbA1c, glycosylated hemoglobin A1c. P0 indicates the differences before and after intervention within the group. P1 indicates the differences between groups after intervention. Pinter represents the p-value for the interaction effect between group and time.