Table 2.
Correlation between log2FC and fatty acyl carbon chain length or degree of unsaturation within each lipid subclass.
| Class | Subclass | Number of lipid species | Carbon chain length | Degree of unsaturation | ||
|---|---|---|---|---|---|---|
| ρ a | p-valueb | ρ a | p-valueb | |||
| Glycerolipids | TG | 108 | 0.692 | <0.001 | 0.407 | <0.001 |
| TG-O | 3 | 0.103 | 0.735 | 0.255 | 0.400 | |
| DG | 5 | 0.353 | 0.559 | −0.666 | 0.218 | |
| Glycerophospholipids | PC | 66 | 0.323 | 0.008 | −0.048 | 0.699 |
| PC-O(P) | 61 | 0.023 | 0.859 | 0.414 | <0.001 | |
| PE | 16 | 0.486 | 0.055 | 0.560 | 0.023 | |
| PE-O(P) | 18 | −0.301 | 0.224 | 0.148 | 0.556 | |
| LPE | 7 | 0.889 | 0.007 | 0.654 | 0.110 | |
| LPC | 28 | 0.747 | <0.001 | 0.584 | <0.001 | |
| LPC-O | 5 | −0.579 | 0.305 | −0.866 | 0.0576 | |
| PI | 16 | 0.463 | 0.070 | 0.120 | 0.656 | |
| Fatty acyls | Car | 17 | −0.118 | 0.651 | −0.078 | 0.764 |
| FA | 13 | −0.118 | 0.651 | −0.078 | 0.764 | |
| Sphingolipids | Cer | 19 | 0.027 | 0.910 | −0.509 | 0.025 |
| HexCer | 8 | −0.709 | 0.074 | 0.669 | 0.099 | |
| Hex2Cer | 5 | 0.447 | 0.450 | 0.577 | 0.308 | |
| SM | 56 | 0.141 | 0.298 | −0.455 | <0.001 | |
| Sterol lipids | CE | 8 | 0.600 | 0.115 | 0.574 | 0.136 |
| ST | 4 | 0.600 | 0.416 | 0.447 | 0.552 | |
Spearman’s correlation coefficients are presented.
p-values were calculated using Spearman’s rank correlation test. TG, triglycerides; TG-O, ether-linked triglycerides; DG, diglycerides; PC, phosphatidylcholine; PC-O(P), ether-linked phosphatidylcholines; PE, phosphatidylethanolamines; PE-O(P), ether-linked phosphatidylethanolamines; LPE, lysophosphatidylethanolamines; LPC, lysophosphatidylcholines; LPC-O, ether-linked lysophosphatidylcholines; PI, phosphatidylinositols; Car, acylcarnitines; FA, fatty acids; Cer, ceramides; HexCer, hexosylceramides; Hex2Cer, dihexosylceramides; SM, sphingomyelins; CE, cholesteryl esters; ST, steroids.