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. 2026 Jun 24;11(9):106679. doi: 10.1016/j.ekir.2026.106679

Figure 2.

Figure 2

Impact of nutritional status at diagnosis on patient and graft survival in KTRs with norovirus infection. (a) Left panel: Kaplan–Meier survival curves for all-cause mortality among kidney transplant recipients with norovirus infection, stratified by nutritional status at diagnosis. Patient survival was significantly lower in patients with severe undernutrition than in those with moderate or no undernutrition (log-rank trend test, P = 0.01). Right panel: IRs and IRRs were calculated using univariable Poisson regression enable subgroup comparisons. Compared with patients without undernutrition, those with severe undernutrition had a significantly increased risk of death (IRR = 2.52 [95% CI: 1.19–5.32], P = 0.016). Multivariable Cox analysis identified severe undernutrition (HR = 3.87 [95% CI: 1.34–11.21], P = 0.0126), age, and diabetes as independent predictors of mortality. (b) Left panel: Kaplan–Meier survival curves for graft loss (return to dialysis) among kidney transplant recipients with norovirus infection, stratified by nutritional status at diagnosis. Patients with severe undernutrition had a higher risk of graft loss (log-rank trend P = 0.012). Right panel: IRs and IRRs were calculated using univariable Poisson regression enable subgroup comparisons. Compared with patients without undernutrition, those with severe undernutrition had a higher risk of graft loss (IRR = 2.32 [95% CI: 0.91–5.91], P = 0.07). In multivariable Cox analysis, severe undernutrition (HR = 2.96 [95% CI: 1.02–8.60], P = 0.0468) and baseline creatinine predicted graft loss. CI, confidence interval; IR, incidence rate; IRR, incidence rate ratios.