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Photographs of Spag6−/− mice (A and B) and a wild-type littermate (A) showing small body with a disproportionately large head in the Spag6-deficient animal. (C) Hydrocephalus in Spag6−/− mice. Sagittal sections of brains from a Spag6-deficient mouse and wild-type mouse revealing dilatation of the lateral and third ventricles in the mutant brain.
