Table 2.
Demographic, laboratory tests and intraoperative details for patients with severe complications.
| Characteristic | Severe complications (n = 132) | No severe complications (n = 800) | P value |
|---|---|---|---|
| Demographic | |||
| Age >65, y | 95 (72.0) | 326 (40.8) | <0.001 |
| Men | 79 (59.8) | 477 (59.6) | 0.961 |
| BMI, kg/m2 | 23.5 ± 3.4 | 23.5 ± 3.2 | 0.973 |
| CCI ≥3 | 12 (9.1) | 42 (5.3) | 0.080 |
| Comorbidities | |||
| Hypertension | 51 (38.6) | 252 (31.5) | 0.105 |
| Diabetes mellitus | 23 (17.4) | 126 (15.8) | 0.805 |
| ASA ≥3 | 93 (70.5) | 342 (42.9) | <0.001 |
| Preoperative NRS2002 ≥2 | 115 (87.1) | 493 (61.6) | <0.001 |
| Chemotherapy history | 0 (0.0) | 12 (1.5) | 0.317 |
| Smoking | 21 (15.9) | 138 (17.3) | 0.704 |
| Laboratory tests | |||
| Preoperative Hct, % | 38.4 (33.6-43.3) | 40.0 (35.6-43.6) | 0.062 |
| Preoperative Hgb, g/L | 125.5 (108.0-143.8) | 132.0 (115.0-146.0) | <0.05 |
| Preoperative Neu, ×10^9/L | 3.4 (2.6-4.5) | 3.4 (2.6-4.3) | 0.715 |
| Preoperative Alb, g/L | 36.3 (33.7-39.5) | 37.9 (35.6-41.0) | <0.001 |
| Nadir Alb within POD 2, g/L | 28.1 (25.3-31.5) | 30.2 (27.6-33.0) | <0.001 |
| △Alb | 22.2 (12.8-31.5) | 19.6 (12.4-27.6) | 0.185 |
| Operative details | |||
| Operation time, median (range), min | 220.0 (50.0-603.0) | 219.0 (63.0-553.0) | 0.630 |
| Type of surgery | <0.05 | ||
| Right colectomy | 30 (22.7) | 108 (13.5) | |
| Transverse colectomy | 0 (0.0) | 2 (0.3) | |
| Left colectomy | 12 (9.1) | 57 (7.1) | |
| Sigmoid resection | 6 (4.5) | 43 (5.4) | |
| Rectal resection | 68 (51.5) | 496 (62.0) | |
| Subtotal colectomy | 1 (0.8) | 0 (0.0) | |
| Abdominoperineal resection | 9 (6.8) | 72 (9.0) | |
| Other | 6 (4.5) | 22 (2.8) | |
| Laparoscopic surgery | 109 (82.6) | 717 (89.6) | <0.05 |
| TNM stage | 0.427 | ||
| I-II | 69 (52.3) | 464 (58.1) | |
| III | 52 (39.4) | 282 (35.3) | |
| IV | 11 (8.3) | 53 (6.6) | |
| Stoma creation | 33 (25.0) | 269 (33.6) | 0.056 |
| Anesthesia details | |||
| Anesthesia Technique | 0.246 | ||
| General anesthesia | 122 (92.4) | 699 (87.4) | |
| Local infiltration with general anesthesia | 4 (3.0) | 42 (5.3) | |
| TAPP with general anesthesia | 6 (4.5) | 59 (7.4) | |
| Sufentanil, median (range), ug | 30.0 (20.0-39.4) | 30.0 (20.0-35.0) | 0.432 |
| Propofol, median (range), mg | 698.3 (549.0-1001.7) | 773.4 (619.1-943.9) | 0.096 |
| Dexmedetomidine, median (range), ug | 43.3 (0.0-74.4) | 51.4 (0.0-77.6) | 0.482 |
| Rocuronium, median (range), mg | 120.0 (90.0-150.0) | 95.0 (75.0-115.0) | <0.001 |
| Intraoperative blood transfusion | 9 (6.8) | 61 (7.6) | 0.860 |
| Intraoperative fluid utilization, median (range), mL | 2275.0 (2000.0-3000.0) | 2000.0 (2000.0-2500.0) | 0.644 |
| Urinary Output, mL | 400.0 (300.0-675.0) | 400.0 (222.5-600.0) | 0.925 |
| Bleeding, mL | 100.0 (85.0-200.0) | 100.0 (50.0-100.0) | <0.05 |
CCI, charlson comorbidity index; NRS2002, nutritional risk screening 2002; Hct, hematocrit; Hgb, hemoglobin; Neut, neutrophils; Alb, albumin; POD, postoperative day; ΔALB, (preoperative Alb – nadir Alb within POD 2)/preoperative ALB × 100%.