Table 2.

Pooled diagnostic performance.

Variables	All studies (n = 15)	Human (n = 11)	Mice (n = 4)
Positive samples, n	1,166	1,048	118
Negative samples, n	1,415	1,329	86
Sensitivity, 95%CI	0.93 (0.81–0.97)	0.91 (0.73–0.97)	0.96 (0.82–0.99)
Specificity, 95%CI	0.90 (0.80–0.95)	0.89 (0.75–0.96)	0.93 (0.81–0.98)
PLR, 95%CI	9.5 (4.5–20.4)	8.6 (3.3–22.5)	14.1 (4.6–42.7)
NLR, 95%CI	0.08 (0.03–0.23)	0.10 (0.03–0.34)	0.05 (0.01–0.22)
DOR, 95%CI	120 (26–543)	86 (14–523)	292 (29–2,962)
AUC, 95%CI	0.96 (0.94–0.98)	0.96 (0.94–0.97)	0.98 (0.96–0.99)