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. 2026 Jul 13;17:1843796. doi: 10.3389/fimmu.2026.1843796

Figure 5.

Panel a shows a heatmap of gene expression data for IFN_LPS_Macrophage and IL4_Macrophage groups at different time points, with genes labeled on the left. Panel b displays a PCA plot of individuals separated by macrophage group, with blue and pink cluster points. Panel c presents a line graph of polarization speed over time intervals for the two macrophage groups. Panel d contains another heatmap of gene expression across day and replicate for various genes. Panel e is a PCA plot with points colored by time point and shaped by replicate. Panel f displays a line graph of speed across time intervals with error bars.

Broad applicability of the CDBGE selector across public datasets. Application of the CDBGE selector to the human macrophage GSE273627 dataset (upper row) and the hESC differentiation GSE274620 dataset (lower row). (A, D), Heatmaps of genes selected using the CDBGE selector. (B, E), PCA plots showing classification of cell groups based on selected markers. (C, F), speed plot of changes in gene dynamics.