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Diagnostic performance of FIB-4 for carotid atherosclerosis.
| Outcome | AUC (95% CI) | Cut-off value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Youden index |
|---|---|---|---|---|---|---|---|
| CAS | 0.579 (0.546–0.616) | 0.94 | 63.7 | 51.2 | 66.0 | 48.6 | 0.149 |
The optimal cut-off value was determined using the maximum Youden index from receiver operating characteristic (ROC) analysis. The 95% confidence interval for AUC was derived by 1,000-iteration bootstrap resampling.
