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. 2026 Jul 13;17:1890018. doi: 10.3389/fendo.2026.1890018

Table 6.

Baseline characteristics before and after propensity score matching in the Non-DSPN and DSPN groups.

Variable Before PSM After PSM
Total
(n = 569)
Non-DSPN
(n = 148)
DSPN
(n = 421)
Statistic P SMD Total
(n = 286)
Non-DSPN
(n = 143)
DSPN
(n = 143)
Statistic P SMD
Age, years 58.36 ± 11.38 55.87 ± 11.44 59.24 ± 11.24 t = -3.117 0.002 0.299 56.43 ± 11.28 56.35 ± 11.23 56.50 ± 11.37 t = -0.115 0.908 0.014
BMI, kg/m² 24.13 ± 3.36 24.51 ± 3.41 24.00 ± 3.34 t = 1.585 0.114 -0.15 24.21 ± 3.45 24.36 ± 3.37 24.05 ± 3.52 t = 0.771 0.442 -0.09
SBP, mmHg 129.35 ± 17.39 127.05 ± 16.46 130.16 ± 17.66 t = -1.871 0.062 0.176 126.89 ± 16.72 127.48 ± 16.40 126.30 ± 17.07 t = 0.597 0.551 -0.07
DBP, mmHg 81.06 ± 10.96 80.94 ± 10.40 81.10 ± 11.17 t = -0.155 0.877 0.015 80.69 ± 10.49 81.02 ± 10.48 80.35 ± 10.52 t = 0.540 0.589 -0.06
HbA1c, % 8.98 ± 2.45 8.79 ± 2.28 9.05 ± 2.51 t = -1.106 0.269 0.103 8.89 ± 2.44 8.78 ± 2.29 9.00 ± 2.59 t = -0.750 0.454 0.084
TC, mmol/L 5.24 ± 1.57 5.15 ± 1.49 5.27 ± 1.59 t = -0.809 0.419 0.076 5.22 ± 1.58 5.18 ± 1.50 5.25 ± 1.65 t = -0.397 0.692 0.045
DM duration, years 7.00 (2.00–10.17) 5.00 (1.00–10.00) 8.00 (3.00–11.00) Z = -3.074 0.002 0.255 6.00 (1.00–10.00) 5.00 (1.00–10.00) 6.00 (2.00–10.00) Z = -0.786 0.432 0.028
TG, mmol/L 1.69 (1.15–2.72) 1.77
(1.15–2.88)
1.68 (1.15–2.63) Z = -0.565 0.572 -0.03 1.71 (1.10–2.79) 1.68 (1.11–2.77) 1.72 (1.10–2.79) Z = -0.226 0.821 0.074
IR 4.03 (2.39–6.30) 3.46
(1.69–5.52)
4.29 (2.59–6.47) Z = -3.056 0.002 0.19 3.57 (1.99–5.40) 3.41 (1.68–5.62) 3.68 (2.38–5.27) Z = -0.745 0.456 -0.09
Gender, n (%) χ² = 3.270 0.071 χ² = 0.063 0.801
Male 353 (62.04) 101 (68.24) 252 (59.86) -0.17 192 (67.13) 97 (67.83) 95 (66.43) -0.03
Female 216 (37.96) 47 (31.76) 169 (40.14) 0.17 94 (32.87) 46 (32.17) 48 (33.57) 0.03
Exercise, n (%) χ² = 0.003 0.958 χ² = 0.014 0.905
No 324 (56.94) 84 (56.76) 240 (57.01) 0.005 163 (56.99) 82 (57.34) 81 (56.64) -0.01
Yes 245 (43.06) 64 (43.24) 181 (42.99) -0.005 123 (43.01) 61 (42.66) 62 (43.36) 0.01
Smoke, n (%) χ² = 0.025 0.875 χ² = 0.000 1.000
No 424 (74.52) 111 (75.00) 313 (74.35) -0.015 214 (74.83) 107 (74.83) 107 (74.83) 0
Yes 145 (25.48) 37 (25.00) 108 (25.65) 0.015 72 (25.17) 36 (25.17) 36 (25.17) 0

Data are presented as mean ± standard deviation, median (interquartile range), or n (%) as appropriate. DSPN, distal symmetric polyneuropathy; PSM, propensity score matching; SMD, standardized mean difference; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, glycated hemoglobin; TC, total cholesterol; DM, diabetes mellitus; TG, triglycerides; IR, insulin resistance.