Table 5.
Factors associated with SDS in patients with MOH.
| Characteristic | B | P-value | 95.0% CI for B | Collinearity statistics | |||
|---|---|---|---|---|---|---|---|
| Lower bound | Upper bound | Tolerance | VIF | ||||
| (Constant) | −2.511 | 0.487 | −9.644 | 4.622 | |||
| Age | 0.037 | 0.239 | −0.025 | 0.098 | 0.715 | 1.399 | |
| Female sex | 0.384 | 0.527 | −0.816 | 1.584 | 0.628 | 1.591 | |
| BMI | −0.015 | 0.758 | −0.111 | 0.081 | 0.782 | 1.279 | |
| Duration of MOH | 0.020 | 0.844 | −0.181 | 0.221 | 0.855 | 1.170 | |
| Type of primary headache disorder | Tension-type headache | −1.112 | 0.063 | −2.287 | 0.063 | 0.759 | 1.317 |
| Cluster headache | −1.385 | 0.163 | −3.337 | 0.567 | 0.740 | 1.352 | |
| MHD | −0.091 | 0.199 | −0.231 | 0.049 | 0.273 | 3.664 | |
| AMD | 0.254 | 0.002* | 0.092 | 0.416 | 0.240 | 4.173 | |
| HIT-6 total score | 0.086 | 0.046* | 0.002 | 0.170 | 0.732 | 1.366 | |
| DASS-12 total score | −0.071 | 0.075 | −0.148 | 0.007 | 0.435 | 2.301 | |
| SURPS total score | 0.031 | 0.368 | −0.037 | 0.100 | 0.448 | 2.234 | |
| Heavy caffeine consumption | −0.460 | 0.544 | −1.955 | 1.035 | 0.476 | 2.102 | |
| CUDQ total score | 0.160 | 0.002* | 0.060 | 0.260 | 0.369 | 2.711 | |
AMD, acute medication days; BMI, body mass index; CUDQ, Caffeine Use Disorder Questionnaire; DASS-12, Depression Anxiety Stress Scales–12; HIT-6, Headache Impact Test–6; MHD, monthly headache days; MOH, medication overuse headache; SDS, Severity of Dependence Scale; SURPS, Substance Use Risk Profile Scale.
Adjusted R square = 0.236.
*P-value < 0.05 is considered significant.