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. 2026 Jul 13;16:1882033. doi: 10.3389/fonc.2026.1882033

Table 2.

The dose objectives for PTV and dose constraints for OARs.

Structures Parameters Dose objectives
PTV1
BCS D95% ≥50 Gy
MRM D95% ≥50 Gy
PTVtb2
BCS D95% ≥10 Gy
Ipsilateral lung
V20 Gy ≤25% ∼ 28%
V5 Gy ≤50% ∼ 60%
MLD3 ≤15 Gy
Heart
Dmean ≤4 Gy ∼ 8 Gy
V5 Gy ≤30% ∼ 40%
Contralateral lung
V5 Gy ≤20%
Contralateral breast
V5 Gy ≤20%
Thyroid gland
Dmean ≤20 Gy
Spinal cord
Dmax ≤20 Gy ∼ 30 Gy
1

BCS, breast-conserving surgery; MRM, modified radical mastectomy; 2tb, tumor bed; 3MLD, mean lung dose.