TABLE 1.
Baseline characteristics and comparative analysis.
| Variables | Total (n = 644) | Survivor (n = 399) | Non-survivor (n = 245) | Statistic | P |
|---|---|---|---|---|---|
| Recurrence type, n (%) | χ2 = 70.44 | <0.001 | |||
| None | 336 (52.17) | 253 (63.41) | 83 (33.88) | – | – |
| ≤1 year | 145 (22.52) | 51 (12.78) | 94 (38.37) | – | – |
| >1 year | 163 (25.31) | 95 (23.81) | 68 (27.76) | – | – |
| Sex, n (%) | χ2 = 0.09 | 0.761 | |||
| Male | 420 (65.22) | 262 (65.66) | 158 (64.49) | – | – |
| Female | 224 (34.78) | 137 (34.34) | 87 (35.51) | – | – |
| Age, n (%) | χ2 = 6.54 | 0.011 | |||
| ≤57 | 354 (54.97) | 235 (58.90) | 119 (48.57) | – | – |
| >57 | 290 (45.03) | 164 (41.10) | 126 (51.43) | – | – |
| BMI, n (%) | χ2 = 0.08 | 0.777 | |||
| ≤22.76 | 438 (68.01) | 273 (68.42) | 165 (67.35) | – | – |
| >22.76 | 206 (31.99) | 126 (31.58) | 80 (32.65) | – | – |
| CEA, n (%) | χ2 = 4.90 | 0.027 | |||
| ≤14.79 | 288 (44.72) | 192 (48.12) | 96 (39.18) | – | – |
| >14.79 | 356 (55.28) | 207 (51.88) | 149 (60.82) | – | – |
| CA199, n (%) | χ2 = 15.51 | <0.001 | |||
| ≤56.99 | 455 (70.65) | 304 (76.19) | 151 (61.63) | – | – |
| >56.99 | 189 (29.35) | 95 (23.81) | 94 (38.37) | – | – |
| TyG, n (%) | χ2 = 3.21 | 0.073 | |||
| Low | 169 (26.24) | 95 (23.81) | 74 (30.20) | – | – |
| High | 475 (73.76) | 304 (76.19) | 171 (69.80) | – | – |
| SII, n (%) | χ2 = 0.90 | 0.342 | |||
| Low | 522 (81.06) | 328 (82.21) | 194 (79.18) | – | – |
| High | 122 (18.94) | 71 (17.79) | 51 (20.82) | – | – |
| SIRI, n (%) | χ2 = 3.31 | 0.069 | |||
| Low | 74 (11.49) | 53 (13.28) | 21 (8.57) | – | – |
| High | 570 (88.51) | 346 (86.72) | 224 (91.43) | – | – |
| Chemotherapy, n (%) | χ2 = 11.90 | <0.001 | |||
| No | 66 (10.25) | 28 (7.02) | 38 (15.51) | – | – |
| Yes | 578 (89.75) | 371 (92.98) | 207 (84.49) | – | – |
| Location, n (%) | χ2 = 0.99 | 0.32 | |||
| Left | 510 (79.19) | 311 (77.94) | 199 (81.22) | – | – |
| Right | 134 (20.81) | 88 (22.06) | 46 (18.78) | – | – |
| pT, n (%) | χ2 = 3.62 | 0.057 | |||
| I and II | 69 (10.71) | 50 (12.53) | 19 (7.76) | – | – |
| III and IV | 575 (89.29) | 349 (87.47) | 226 (92.24) | – | – |
| pN, n (%) | χ2 = 30.72 | <0.001 | |||
| No | 222 (34.47) | 170 (42.61) | 52 (21.22) | – | – |
| Yes | 422 (65.53) | 229 (57.39) | 193 (78.78) | – | – |
| Differentiation, n (%) | χ2 = 4.19 | 0.041 | |||
| Middle and high | 530 (82.30) | 338 (84.71) | 192 (78.37) | – | – |
| Low | 114 (17.70) | 61 (15.29) | 53 (21.63) | – | – |
| Cancer thrombus, n (%) | χ2 = 5.25 | 0.022 | |||
| No | 494 (76.71) | 318 (79.70) | 176 (71.84) | – | – |
| Yes | 150 (23.29) | 81 (20.30) | 69 (28.16) | – | – |
| Neural infiltration, n (%) | χ2 = 0.98 | 0.322 | |||
| No | 433 (67.24) | 274 (68.67) | 159 (64.90) | – | – |
| Yes | 211 (32.76) | 125 (31.33) | 86 (35.10) | – | – |
| Ki67 level, n (%) | χ2 = 14.57 | <0.001 | |||
| >0.5 | 283 (43.94) | 152 (38.10) | 131 (53.47) | – | – |
| ≤0.5 | 361 (56.06) | 247 (61.90) | 114 (46.53) | – | – |
| Her2, n (%) | χ2 = 2.32 | 0.128 | |||
| No | 494 (76.71) | 314 (78.70) | 180 (73.47) | – | – |
| Yes | 150 (23.29) | 85 (21.30) | 65 (26.53) | – | – |
| Kras mutation, n (%) | χ2 = 3.84 | 0.05 | |||
| No | 529 (82.14) | 337 (84.46) | 192 (78.37) | – | – |
| Yes | 115 (17.86) | 62 (15.54) | 53 (21.63) | – | – |
| Number of live metastases, n (%) | χ2 = 7.81 | 0.005 | |||
| ≤2 | 414 (64.29) | 273 (68.42) | 141 (57.55) | – | – |
| >2 | 230 (35.71) | 126 (31.58) | 104 (42.45) | – | – |
| Site of liver metastases, n (%) | χ2 = 2.49 | 0.114 | |||
| Single | 380 (59.01) | 245 (61.40) | 135 (55.10) | – | – |
| Double | 264 (40.99) | 154 (38.60) | 110 (44.90) | – | – |
| Maximum diameter of liver metastasis, n (%) | χ2 = 1.59 | 0.207 | |||
| ≤2.8 | 110 (17.08) | 74 (18.55) | 36 (14.69) | – | – |
| >2.8 | 534 (82.92) | 325 (81.45) | 209 (85.31) | – | – |
| CRS level, n (%) | χ2 = 31.37 | <0.001 | |||
| High | 102 (15.84) | 38 (9.52) | 64 (26.12) | – | – |
| Low | 542 (84.16) | 361 (90.48) | 181 (73.88) | – | – |
| Treatment of liver metastases, n (%) | χ2 = 2.97 | 0.227 | |||
| Surgery | 248 (38.51) | 154 (38.60) | 94 (38.37) | – | – |
| Ablation | 327 (50.78) | 196 (49.12) | 131 (53.47) | – | – |
| Both | 69 (10.71) | 49 (12.28) | 20 (8.16) | – | – |
χ2, Chi-square test.