Table 1.
Clinical and demographic characteristics of the Benign, AH, and EC groups (n=185).
| Variable | Benign | AH | EC | P_overall | P_Benign vs AH | P_Benign vs EC | P_AH vs EC |
|---|---|---|---|---|---|---|---|
| n | 125 | 34 | 26 | ||||
| Age (yrs) | 31.88 (5.27) |
31.21 (4.72) |
31.88 (4.11) |
0.791 | |||
| BMI | 26.7 (5.2) |
28.8 (5.21) |
28.08 (5.89) |
0.181 | |||
| HOMA_IR | 3.54 (2.39) |
5.91 (4.80) |
5.57 (6.11) |
0.031 | 0.009 | 0.375 | 0.172 |
| FPG (mmol/L) | 5.03 (0.57) |
5.6 (1.76) |
5.46 (1.51) |
0.025 | 0.041 | 0.885 | 0.188 |
| HDL_C (mmol/L) | 1.39 (0.43) |
1.14 (0.22) |
1.19 (0.25) |
0.005 | 0.01 | 0.885 | 0.06 |
| FAI | 8.64 (6.63) |
9.72 (9.40) |
6.34 (6.58) |
0.371 | |||
| OGTT_2h (mmol/L) | 7.46 (2.4) |
9.30 (4.24) |
8.24 (3.53) |
0.049 | 0.043 | 0.498 | 0.555 |
| FINS (pmol/L) | 92.33 (55.56) |
136.81 (94.83) |
122.62 (100.84) |
0.021 | 0.027 | 0.781 | 0.208 |
| FSH (mIU/mL) | 6.64 (2.13) |
5.62 (1.93) |
6.52 (2.05) |
0.08 | |||
| LH (mIU/mL) | 10.58 (6.7) |
7.22 (4.33) |
8.7 (6.54) |
0.039 | 0.039 | 0.694 | 0.433 |
| E2 (pmol/L) | 189.31 (180.17) |
183.77 (130.88) |
157.52 (86.54) |
0.729 | |||
| PRL (mIU/mL) | 274.28 (149.92) |
232.13 (123.32) |
598.11 (982.92) |
0.005 | 0.841 | 0.006 | 0.006 |
| OH17P (ng/mL) | 1.02 (1.88) |
0.89 (0.9) |
0.95 (0.59) |
0.977 | |||
| AMH (ng/mL) | 8.3 (5.92) |
7.15 (5.41) |
9.41 (6.19) |
0.398 | |||
| TG (mmol/L) | 1.55 (0.76) |
1.83 (1.12) |
1.43 (0.89) |
0.231 | |||
| TC (mmol/L) | 4.88 (0.97) |
4.95 (0.97) |
4.88 (0.8) |
0.953 | |||
| LDL_C (mmol/L) | 3.28 (0.88) |
3.54 (1.03) |
3.43 (0.86) |
0.46 |
AH, atypical hyperplasia; AMH, anti-Müllerian hormone; BMI, body mass index; EC, endometrial carcinoma; E2, estradiol; FAI, free androgen index; FINS, fasting insulin; FPG, fasting plasma glucose; FSH, follicle-stimulating hormone; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; LH, luteinizing hormone; LDL-C, low-density lipoprotein cholesterol; OGTT-2h, 2-hour oral glucose tolerance test; OH17P, 17α-hydroxyprogesterone; PRL, prolactin; TC, total cholesterol; TG, triglycerides.