Table 4.
Differential expression of key skin barrier and inflammatory genes.
| Gene | Function | G2 (LPS) log2FC | G6 (Consortium) log2FC | Adjusted p-value |
|---|---|---|---|---|
| FLG | Skin barrier formation | -1.86 | +1.32 | <0.01 |
| LOR | Epidermal differentiation | -1.52 | +1.18 | <0.01 |
| IVL | Cornified envelope protein | -1.24 | +0.96 | <0.05 |
| TNF | Pro-inflammatory cytokine | +2.41 | -1.22 | <0.01 |
| IL6 | Inflammatory mediator | +2.18 | -1.04 | <0.01 |
| IL1B | Immune signaling | +1.96 | -0.92 | <0.05 |
Differentially expressed genes were identified using DESeq2 with thresholds of |log2FC| ≥ 1 and FDR-adjusted p < 0.05.