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. 2026 Jul 13;16:1834120. doi: 10.3389/fcimb.2026.1834120

Table 5.

Relative expression of skin barrier genes.

Group FLG (fold change) LOR (fold change) IVL (fold change)
G1 (Control) 1.00 ± 0.05 1.00 ± 0.06 1.00 ± 0.04
G2 (LPS) 0.42 ± 0.03 0.48 ± 0.04 0.53 ± 0.03
G3 (PME 25%) 0.65 ± 0.04 0.71 ± 0.05 0.74 ± 0.04
G4 (PME 50%) 0.86 ± 0.05 0.89 ± 0.05 0.92 ± 0.04
G5 (PME 75%) 1.12 ± 0.06 1.16 ± 0.05 1.14 ± 0.05
G6 (Consortium) 1.28 ± 0.07 1.31 ± 0.06 1.29 ± 0.05

Values represent mean ± SD from three independent biological replicates. Relative expression levels were normalized to GAPDH using the 2-ΔΔCt method. Statistical significance was determined using one-way ANOVA followed by Tukey’s post hoc test (*p < 0.05, **p < 0.01 vs. G2).