Table 3.

Descriptive comparison of patients with and without postoperative CSF leak.

Characteristic	No postoperative leak (n = 210)	Postoperative (n = 3)
Age (mean ± SD)	52.63 ± 13.04	51.7 ± 10.50
Female	124 (59.05%)	2 (66.67%)
Macroadenoma/giant adenomas	183 (87.14%)	3 (100%)
Knosp grade 3-4	51 (24.29%)	2 (66.67%)
Intraoperative leak (any grade)	94 (44.76%)	3 (100%)
Grade 1	40 (19.05%)	1 (33.33%)
Grade 2	43 (20.48%)	2 (66.67%)
Grade 3	11 (5.24%)	0 (0%)

No inferential statistical testing was performed due to the small number of events (n = 3). Moreover, the number of Grade 3 intraoperative leaks (n = 11) is too small to support any conclusion regarding efficacy in high-flow defects. Data are presented descriptively only.