Table 2.
Cardiovascular variables following etorphine and naltrexone injection.
| Timepoint | HR | MAP | MPAP |
|---|---|---|---|
| Baseline (etorphine) | 75 | 96 | 16 |
| 1 | 74 | 96 | 17 |
| 2 | 73 | 96 | 19 |
| 3 | 71 | 102 | 19 |
| 4 | 72 | 106 | 20 |
| 5 | / | / | / |
| 6 | / | / | / |
| 7 | 91 | 96 | 24 |
| 8 | 100 | 94 | 25 |
| 9 | 109 | 95 | 27 |
| 10 | 115 | 95 | 29 |
| Baseline (naltrexone) | 107 | 103 | 24 |
| 1 | 84 | 123 | 29 |
| 2 | 79 | 123 | 27 |
| 3 | 82 | 113 | 25 |
| 4 | 79 | 115 | 22 |
| 5 | / | / | / |
| 6 | / | / | / |
| 7 | 80 | 109 | 17 |
| 8 | 79 | 108 | 20 |
| 9 | 81 | 109 | 21 |
| 10 | 70 | 107 | 18 |
Data are expressed as the median of six sheep at each minute post-administration. Baseline is represented by the pooled median of the measurements obtained from the 5-min before drug injection. Measurements were unavailable 5 and 6 min after both drugs in five of the six sheep due to arterial blood gas sampling and catheter line flushing. Heart rate = HR (beats per minute - bpm); mean arterial pressure = MAP (mmHg); mean pulmonary arterial pressure = MPAP (mmHg).