Table 3.

Subgroup analyses of the association between serum adropin and DKD.

Method/Group	Model 1		Model 2		Model 3
	OR/HR (95% CI)	P-value	OR/HR (95% CI)	P-value	OR/HR (95% CI)	P-value
Logistic
Sex
male	0.74 (0.57, 0.95)	0.018	0.75 (0.58, 0.97)	0.026	0.74 (0.56, 0.96)	0.023
female	0.87 (0.72, 1.05)	0.146	0.87 (0.72, 1.05)	0.150	0.88 (0.73, 1.06)	0.181
Age
≤60	0.75 (0.59, 0.94)	0.012	0.75 (0.59, 0.94)	0.012	0.74 (0.59, 0.94)	0.014
>60	0.89 (0.73, 1.09)	0.261	0.90 (0.73, 1.1)	0.294	0.90 (0.73, 1.10)	0.298
Cox
Sex
male	0.90 (0.84, 0.96)	0.001	0.90 (0.85, 0.96)	0.001	0.90 (0.85, 0.96)	0.001
female	0.87 (0.83, 0.91)	<0.001	0.87 (0.83, 0.91)	<0.001	0.87 (0.83, 0.91)	<0.001
Age
≤60	0.87 (0.81, 0.93)	<0.001	0.87 (0.81, 0.93)	<0.001	0.87 (0.81, 0.93)	<0.001
>60	0.88 (0.84, 0.92)	<0.001	0.89 (0.85, 0.93)	<0.001	0.89 (0.84, 0.93)	<0.001

a Model 1 was an unadjusted model including only Adropin.

b Model 2 was adjusted for age, sex, body mass index (BMI), smoking status, and alcohol consumption.

c Model 3 was further adjusted for hypertension and medication use based on Model.