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. 2026 Jul 13;16:1867715. doi: 10.3389/fonc.2026.1867715

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Copyright © 2026 Li, Liu, Xu, Fang, Sun, Yan, Cao and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Scatter plot showing overall survival in months versus D90 in Gray units. Green circles represent death, blue circles represent censored data. A linear regression line and its equation y = -3.39 + 0.11*x are displayed. — Scatter plot of D90 versus overall survival. Green circles indicate death, and blue circles represent censored patients. The solid line shows the linear regression fit (y = -3.39 + 0.11x). Spearman correlation analysis demonstrated a moderate positive correlation (r = 0.448, P < 0.001), confirming a dose-response relationship between D90 and overall survival.