Table 5.
Characteristics of radiation-induced brain edema.
| Characteristic | 120–140 Gy (n = 2) |
140–160 Gy (n = 10) |
Total (N = 12) |
|---|---|---|---|
| Edema Grade | |||
| Grade 2 | 2 | 7 | 9 |
| Grade 3 | 0 | 3 | 3 |
| Time to onset (weeks), median (range) | 2 (1-3) | 2 (1-4) | 2 (1-4) |
| Duration (weeks), median (range) | 2.5 (2-3) | 2.5 (2-4) | 2.5 (2-4) |
| Hospitalization required | 0 | 2 | 2 |
| Neurological symptoms | |||
| Headache | 2 | 6 | 8 |
| Nausea/vomiting | 1 | 2 | 3 |
| Seizures | 0 | 1 | 1 |
| Motor deficit | 0 | 2 | 2 |
| Speech disturbance | 1 | 0 | 1 |
| Medications | |||
| Mannitol | 2 | 10 | 12 |
| Corticosteroids | 2 | 10 | 12 |
| Antiepileptics | 0 | 1 | 1 |